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role of hyaluronic acid in wound healing

مرهم-للحروق

Comedo cream for wound healing and burns  

Whether you burn your hand on a pan of cookies, spend too much time in the sun, or spill hot coffee on your lap, burns are certainly not pleasant. Unfortunately, burns and wound are one of the most common household injuries.

Burns are categorized by their severity.

A first-degree burn is considered the least severe because it only affects the outer layer of skin. It usually only causes mild pain, redness, and swelling.

Second-degree affect deeper layers of the skin and cause blisters and white, wet, and shiny skin. Third-degree involve damage to all layers of the skin,

fourth-degree may involve the joints and bones. Third- and fourth-degree burns are considered medical emergencies and should only be treated in a hospital.

You can treat most first-degree and second-degree less than three inches in diameter at home. Read on to learn which remedies are best for healing your skin, and also which remedies should be avoided.

manage the burns as fast as possible to avoid scares and infection 

you can depend on comedo cream to heal wound and burns as it contains very effective ingredients including hyaluronic acid , clanduola , panthenol, vitamin E and honey, with hyaluronic play a major role in wound healing as it interacts with the 3 phases of burns healing 

 

The Role of Hyaluronic Acid in burn and wound Healing

Inflammatory phase

•activates cell migration (fibroblasts, lymphocytes, and polynuclear neutrophils) in the Wound site.

•Regulate Inflammation by producing pro-inflammatory cytokines •Stimulate Angiogenesis

Proliferative phase

•accelerates repair mechanisms such as migration and proliferation of fibroblasts, collagen synthesis, and endothelial cells 

Remodeling phase

•Activate the proliferation and migration of keratinocytes and promotes collagen remodeling 

•inhibits the inflammatory reaction, causing a reduction in
fibrosis and therefore fibrous tissue

•Reduce scar formation

wound and  burn - hyaluronic


Several  studies have shown that :

 topical application of HA significantly enhances the wound healing process







resources:

The role of hyaluronic acid in wound healing: assessment of clinical evidence

Exogenous hyaluronic acid and wound healing: an updated vision

 

 

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